ncRNA name | hsa-miR-143 |
ncRNA Category | miRNA |
Disease name | retinoblastoma (RB) |
Species | Homo sapiens |
Tissues/Cell_line | retinas; RB cell lines Y79 and Weri1 |
Methods | transfection, RT-PCR, Western blot, luciferase reporter assay, CCK-8 assay, flow cytometry, transwell assay |
Expression pattern | down-regulated |
Functional description | The microRNA-143 expression was significantly suppressed in RB cell lines. Overexpression of microRNA-143 significantly lowered cell viability and invasion of the RB cell lines, and increased the number of apoptotic cells. |
PubMed ID | 27990360 |
Year | 2016 |
Title | Suppressive effect of microRNA-143 in retinoblastoma. |
Drug-related ncRNA | NO |
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