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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of retinoblastoma (RB)
ncRNA name hsa-miR-143
ncRNA Category miRNA
Disease name retinoblastoma (RB)
Species Homo sapiens
Tissues/Cell_line retinas; RB cell lines Y79 and Weri1
Methods transfection, RT-PCR, Western blot, luciferase reporter assay, CCK-8 assay, flow cytometry, transwell assay
Expression pattern down-regulated
Functional description The microRNA-143 expression was significantly suppressed in RB cell lines. Overexpression of microRNA-143 significantly lowered cell viability and invasion of the RB cell lines, and increased the number of apoptotic cells.
PubMed ID 27990360
Year 2016
Title Suppressive effect of microRNA-143 in retinoblastoma.
Drug-related ncRNA NO

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